2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100046S1
    Nordoxepin-d4 hydrochloride
    		99.90%
    Nordoxepin-d4 (Desmethyldoxepin-d4) hydrochloride is deuterium-labeled Nordoxepin (hydrochloride) (HY-100046).
    Nordoxepin-d<sub>4</sub> hydrochloride
  • HY-155792
    Troglitazone glucuronide
    Troglitazone glucuronide (Compound M2) is an initial metabolite of troglitazone in the liver.
    Troglitazone glucuronide
  • HY-G0014
    Quetiapine sulfoxide
    Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.
    Quetiapine sulfoxide
  • HY-W009512
    CVT-2738
    		99.81%
    CVT-2738 is an orally active metabolite of Ranolazine (HY-B0280). CVT-2738 has a protective effect against Isoprenaline (HY-108353)-induced myocardial ischemia in mice. CVT-2738 can be used in myocardial ischemia research.
    CVT-2738
  • HY-W778340
    16α-Hydroxy-11-keto prednisolone
    16α-Hydroxy-11-keto prednisolone (compound M-X) is a metabolite of Budesonide (HY-13580). Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide is a widely used for study of asthma, rhinitis, and inflammatory bowel disease.
    16α-Hydroxy-11-keto prednisolone
  • HY-131314
    Ibuprofen carboxylic acid
    Ibuprofen carboxylic acid is the metabolite of Ibuprofen (HY-78131), that has high concentrations in wastewater and water environments, and disappears fast during biodegradation, compared to the other ibuprofen metabolite.
    Ibuprofen carboxylic acid
  • HY-111177R
    Pheneturide (Standard)
    Pheneturide (Standard) is the analytical standard of Pheneturide. This product is intended for research and analytical applications. Pheneturide (Ethylphenacemide, M 551), a decarboxylation product of Phenobarbital, can be used to prevent psychomotor seizures.
    Pheneturide (Standard)
  • HY-W007077
    (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone
    		Control 99.64%
    (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone is a precursor in the synthesis of benzodiazepines and is also a hydrolysis product of Clonazepam.
    (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone
  • HY-W509381
    4-Hydroxyindole-3-acetic acid
    4-Hydroxyindole-3-acetic acid (4HIAA) is a metabolite of Psilocybin and Psilocin.
    4-Hydroxyindole-3-acetic acid
  • HY-G0009
    Ritonavir metabolite
    		99.09%
    Ritonavir metabolite is a metabolite of Ritonavir, which is a HIV protease inhibitor.
    Ritonavir metabolite
  • HY-W016033
    Pantoprazole sulfide
    		98.83%
    Pantoprazole sulfide is a metabolite of Pantoprazole (HY-17507), which is a proton-pump inhibitor.
    Pantoprazole sulfide
  • HY-W017115
    4-Methoxybenzenecarbothioamide
    4-Methoxybenzenecarbothioamide is a synthetic intermediate useful for pharmaceutical synthesis, which can be synthesized by 4-methoxy benzamide and phosphorus pentasulfide reactions.
    4-Methoxybenzenecarbothioamide
  • HY-113257
    Dopamine 4-sulfate
    Dopamine 4-sulfate (DA-4S) is an inactive metabolite of the catecholamine dopamine. It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3. Dopamine 4-O-sulfate is found at lower levels in the brain and circulation than dopamine 3-O-sulfate.
    Dopamine 4-sulfate
  • HY-W099331
    Monoethylglycinexylidide hydrochloride
    Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide has proven to be a highly sensitive indicator of hepatic dysfunction, especially in the field of liver transplantation.
    Monoethylglycinexylidide hydrochloride
  • HY-129072
    Isocyclosporin A
    		98.5%
    Isocyclosporin A is a degradation product of the immunosuppressant Cyclosporin A.
    Isocyclosporin A
  • HY-W010593
    Ethylenethiourea
    		≥98.0%
    Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active.
    Ethylenethiourea
  • HY-W016221S1
    6-Hydroxy Chlorzoxazone-15N,d2
    6-Hydroxy Chlorzoxazone-15N,d2 is the 15N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221).
    6-Hydroxy Chlorzoxazone-<sup>15</sup>N,d<sub>2</sub>
  • HY-N15317
    Phocaecholic acid
    		≥98.0%
    Phocaecholic acid (β-Phocaecholic acid) is a bile acid found in duck bile. Phocaecholic acid can be excreted into bile and partially decarboxylated to nor-chenodeoxycholic acid in rats. Phocaecholic acid is promising for research of bile acid metabolism and related diseases.
    Phocaecholic acid
  • HY-G0003
    Iloperidone metabolite Hydroxy Iloperidone
    		99.97%
    Iloperidone metabolite Hydroxy Iloperidone (P88; Hydroxy Iloperidone) is a metabolite of Iloperidone, which is an atypical antipsychotic.
    Iloperidone metabolite Hydroxy Iloperidone
  • HY-W045132
    N-Desbutyl Bupivacaine
    N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist.
    N-Desbutyl Bupivacaine
Cat. No. Product Name / Synonyms Application Reactivity